Known for his great physical power, he is best remembered for his time with Bayern Munich, whom he represented for over a decade, winning a total of 14 honours, and playing in nearly 250 official matches.
He featured in five Africa Cup of Nations tournaments with the Black Stars
Kuffour was also part of the historic Ghana squad that played at the 2006 FIFA World Cup in Germany.
The former King Faisal Babes player played for the various junior national teams of Ghana before moving to Europe to continue his career.
A message from CAF to celebrate the former Ghana International read: "Enjoy your day, big Sammy!"
Read Full Story???????? Happy birthday to former Ghana star, Samuel Kuffor! ????????
— CAF (@CAF_Online) September 3, 2020
Enjoy your day, big Sammy! ???? pic.twitter.com/rNvTkJHLTF
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