Luciano Spalletti's side inflicted a 4-0 heavy home defeat on Genoa at the Estadio de Luigi Ferraris.
Two-goal hero Roberto Gagliardini opened the floodgate for the Black and Blue lads on the 15th minute from Asamoah's cross.
Other goals were scored by Argentine forward, Mauro Icardi and Ivan Perisic.
Asamoah lasted for the entire duration of the game with another five-star performance.
The 30-year-old has scored once with an assist in his 36 appearances for Inter Milan in all competition
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